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Volume 13 Issue 6
Nov.  2022
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PAN Xiaojun, CHEN Dechang. Gut Microbiota in Hemodynamics[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 936-941. DOI: 10.12290/xhyxzz.2022-0468
Citation: PAN Xiaojun, CHEN Dechang. Gut Microbiota in Hemodynamics[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 936-941. DOI: 10.12290/xhyxzz.2022-0468
shu

Gut Microbiota in Hemodynamics

  • Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Funds: 

National Natural Science Foundation of China 81873944

National Natural Science Foundation of China 82172152

Shanghai Science and Technology Commission 20DZ2200500

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  • Corresponding author:

    CHEN Dechang, E-mail: cdc12064@rjh.com.cn

  • Received Date: August 23, 2022
  • Accepted Date: October 19, 2022
  • Available Online: October 26, 2022
  • Issue Publish Date: November 29, 2022
    Graphical Abstract
    • Abstract
  • The gut microbiota is a powerful "organ" composed of prokaryotic organisms (bacteria), eukaryotic microorganisms (including fungi and protozoa) and viruses, which plays a crucial role in the nutrition metabolism, maintenance of the integrity of intestinal mucosal barrier, and immune regulation of the body. Researches have shown that intestinal microecology is related to the pathogenesis of many diseases, such as neuropsychiatric diseases, autoimmune diseases, cancer and chronic metabolic diseases. Recent studies have found that gut microbiota can regulate hemodynamics through the oxidation of trimethylamine and short chain fatty acids. At the same time, gut microbiota disorder and translocation can activate the body's inflammatory response, affecting the stability of the body's hemodynamics.In this article, we summarize the relationship between gut microbiota and hemodymamics, in order to provide reference for further research.
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