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Volume 13 Issue 1
Jan.  2022
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YANG Jingyi, XU Qianyue, YU Hong. Research Progress on Pathogenesis and Treatment of Juvenile Localized Scleroderma[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(1): 110-116. DOI: 10.12290/xhyxzz.2021-0178
Citation: YANG Jingyi, XU Qianyue, YU Hong. Research Progress on Pathogenesis and Treatment of Juvenile Localized Scleroderma[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(1): 110-116. DOI: 10.12290/xhyxzz.2021-0178
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Research Progress on Pathogenesis and Treatment of Juvenile Localized Scleroderma

  • Department of Dermatology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China

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  • Corresponding author:

    YU Hong, E-mail: yuhong@xinhuamed.com.cn

  • Received Date: February 05, 2021
  • Accepted Date: March 09, 2021
  • Available Online: December 15, 2021
  • Issue Publish Date: January 29, 2022
    Graphical Abstract
    • Abstract
  • Juvenile localized scleroderma (JLS) is a rare autoimmune disease in children. The lack of specificity in the early symptoms of JLS makes it easy to be misdiagnosed and missed, which leads to the continuous progression of the lesions, and even causes systemic malfunction and growth disorder. For identifying the etiology of JLS and guiding the development and application of effective therapeutic drugs, we reviewed recent theories about the pathogenesis of JLS and summarized the traditional treatment options and relevant new therapeutic drugs, aiming to further enhance the fundamental understanding of JLS and its therapeutic progress.
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    • References (53)
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