Microchip as a Controlled Drug Delivery Device Vachhani Savan*, Patel Nikhil, Patel Jatin, Prajapati ST, Patel CN Department of Pharmaceutics and Pharmaceutical Technology, Shri Sarvajanik Pharmacy College, Near Arvind Baug, Mehsana-384 001, India *Corresponding Author E-mail: savan_2011@yahoo.com
Online published on 3 April, 2013. Abstract Controlled-release systems are common in a number of products areas, including foods, cosmetics, pesticides and paper. Controlled-release system for a drug delivery first appeared in 1960s and 1970s. In the past three decades, the number and variety of controlled release systems for drug delivery application has increased dramatically. Many of these use polymers having particular physical or chemical characteristics such as biodegradability, biocompatibility or responsiveness to pH or temperature changes. However, recent advances in the field of microfabrication have created the possibility of a new class of controlled release system for drug delivery, namely, that of small, programmable devices. there small size, potential for integration with micro-electronics, and ability to store and release chemical on a demand could make controlled-release microchips useful in a number of areas, including medical diagnostics, analytical chemistry, chemical detection, industrial process monitoring and control, combinatorial chemistry, microbiology and fragrance delivery. More importantly, microfabrication technology may provide new treatment options to clinicians in their fight against disease. Top Keywords Controlled-release drug delivery, Microchips, Implant, Microfabrication process. Top |