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Volume 13 Issue 6
Nov.  2022
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WANG Yuxin, GUO Xiaoxiao, YANG Deyan, ZHAO Jiuliang, JIANG Ying, HU Rongrong, SHEN Dongchao, MAO Yueying, WANG Lin, YAN Xiaowei. Coronary Aneurysm-like Dilation with Stenosis, Anti-phospholipid Antibody Syndrome, Nephrotic Syndrome, and Polycystic Kidney: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 1069-1073. DOI: 10.12290/xhyxzz.2021-0678
Citation: WANG Yuxin, GUO Xiaoxiao, YANG Deyan, ZHAO Jiuliang, JIANG Ying, HU Rongrong, SHEN Dongchao, MAO Yueying, WANG Lin, YAN Xiaowei. Coronary Aneurysm-like Dilation with Stenosis, Anti-phospholipid Antibody Syndrome, Nephrotic Syndrome, and Polycystic Kidney: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 1069-1073. DOI: 10.12290/xhyxzz.2021-0678
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Coronary Aneurysm-like Dilation with Stenosis, Anti-phospholipid Antibody Syndrome, Nephrotic Syndrome, and Polycystic Kidney: A Case Report

  • 1.

    Department of Pulmonary and Critical Care Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    Department of Cardiology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 3.

    Department of Rheumatology and Clinical Immunology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 4.

    Department of Nephrology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 5.

    Department of Neurology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 6.

    Department of Hematopathology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 7.

    Department of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds: 

National High Level Hospital Clinical Research Funding 2022-PUMCH-A-182

More Information
  • Corresponding author:

    GUO Xiaoxiao, E-mail: xiaoxiaoguopumch@163.com

  • Received Date: October 02, 2021
  • Accepted Date: November 25, 2021
  • Available Online: July 28, 2022
  • Issue Publish Date: November 29, 2022
    Graphical Abstract
    • Abstract
  • Here we report a case that a young man had early onset myocardial infarction. Coronary angiography showed coronary aneurysm-like dilation and thromboembolism. After stents were implanted, his condition was complicated with repeated stent restenosis. Polycystic kidney, nephrotic syndrome and antiphospholipid antibody syndrome were also present. Antiphospholipid antibody syndrome, a risk factor for recurrent coronary thrombosis, can lead to nephrotic syndrome. Polycystic kidney can be characterized by nephrotic syndrome and may be combined with aneurysmal lesions due to genetic abnormalities. According to the multidisciplinary discussion and follow-up results, the patient was diagnosed as connective tissue diseases and secondary anti-phospholipid antibody syndrome, nephrotic syndrome, and coronary artery lesions. The patient's symptoms improved after treatment for the original disease. The management of this patient broadened our understanding of the etiology of coronary artery disease in young patients and demonstrated the importance of multidisciplinary clinical thinking.
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    • References (11)
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