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Volume 14 Issue 4
Jul.  2023
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SHI Xiuqing, YAN Siyu, HUANG Qiao, LI Xuhui, WANG Yongbo, MA Wenhao, SHANG Hongcai, JIN Yinghui. Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(4): 859-867. DOI: 10.12290/xhyxzz.2022-0217
Citation: SHI Xiuqing, YAN Siyu, HUANG Qiao, LI Xuhui, WANG Yongbo, MA Wenhao, SHANG Hongcai, JIN Yinghui. Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(4): 859-867. DOI: 10.12290/xhyxzz.2022-0217
shu

Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making

  • 1.

    Department of Oncology, Yuhuangding Hospital of Yantai, Yantai, Shandong 264000, China

  • 2.

    Center for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

  • 3.

    Zhongnan Hospital of Wuhan University, Wuhan 430071, China

  • 4.

    Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine, Ministry of Education and Beijing Key Laboratory of Internal Medicine of Traditional Chinese Medicine, Beijing 100700, China

Funds: 

National Natural Science Foundation of China 82174230

More Information
  • Corresponding author:

    SHANG Hongcai, E-mail: shanghongcai@126.com

    JIN Yinghui, E-mail: jinyinghuiebm@163.com

  • Received Date: April 19, 2022
  • Accepted Date: June 12, 2022
  • Available Online: October 09, 2022
  • Issue Publish Date: July 29, 2023
    Graphical Abstract
    • Abstract
  • Clinical practice guidelines are an important basis for clinical decision-making, but there are still many factors that prevent physicians from following the guidelines. One of the problems, the limited external validity of the guidelines, ultimately prevents the guidelines from providing an adequate basis for clinical decision-making, thus forming the gap between the guidelines and clinical decisions. Real-world research can enhance the external validity of the guidelines, provide a basis for clinical decision-making, and offer localized evidence for the guidelines, evidence of cost-effectiveness and other evidence for the guidelines. It can also monitor the implementation of the guidelines and help to make up for the lack of evidence in the formulation of traditional guidelines. Therefore, high-quality real-world studies and real-world evidence may be considered in the guideline development process to facilitate guideline optimization and serve as an aid to guideline quality improvement.
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    • References (65)
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